最近的一些研究发现,暴发性乙型肝炎(FHB)患者的δ标志发生率明显高于普通的急性乙型病毒性肝炎患者。在有δ标志的FHB 患者中,42%是在 HBV 无症状携带基础上出现伴有急性δ因子迭加感染的暴发过程。对黑猩猩所作的动物实验也表明,急性δ感染迭加于原先存在的 HBV 感染时,肝坏死较同时发生急性δ和 HBV 感染时更为严重。为了探讨 FHB 中δ因子的作用,作者对 Some recent studies have found that the incidence of δ-sign in patients with fulminant hepatitis B (FHB) is significantly higher than in patients with normal acute hepatitis B virus. 42% of FHB patients with a δ-marker were experiencing an outbreak of acute delta-factor coinfection on the basis of HBV asymptomatic carriage. Animal experiments on chimpanzees have also shown that acute delta infection is more severe in patients with preexisting HBV infection than when both acute delta and HBV infection occur simultaneously. To investigate the role of delta-factor in FHB, the authors right