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目的观察抑郁症患者局部大脑皮层血流灌注异常类型。方法选择未治疗的按CCMD鄄2鄄R标准诊断为抑郁症患者12例,进行脑双半胱乙酯(ECD)显像,并与19名年龄匹配的健康人作比较,用统计参数图(SPM)对图像进行分析。结果SPM分析显示双侧额叶、左侧颞上回、左侧边缘叶钩回(Brodmannarea20)、左侧丘脑乳头体、右侧扣带回、右侧壳核血流下降。结论抑郁症患者额叶、颞叶及边缘系统局部脑血流明显降低。
Objective To observe the abnormal cerebral blood flow perfusion in patients with depression. Methods Twelve patients who were diagnosed as depression by untreated CCMD Juan 2 R criteria were enrolled in this study. Encephalo-ethylamine (ECD) imaging was performed and compared with 19 age-matched healthy subjects. SPM) to analyze the image. Results SPM analysis showed that bilateral frontal lobe, left superior temporal gyrus, left lateral lobular gyrus (Brodmannarea20), left thalamus papillary body, right cingulate gyrus and right putamen decreased. Conclusion Local cerebral blood flow in frontal lobe, temporal lobe and limbic system is significantly decreased in patients with depression.