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人类正常妊娠过程中,胎儿绒毛外滋养层细胞必须侵入到子宫蜕膜中。滋养层细胞表达非典型I类HLA分子,如HLA-G等。这些滋养层细胞如何不被母亲效应细胞攻击,目前还未了解。蜕膜中存在一大群CD_3~-的大颗粒淋巴细胞(LGL),其与
During normal human pregnancy, fetal villi trophoblast cells must invade the uterine decidua. Trophoblast cells express atypical class I HLA molecules such as HLA-G and the like. How trophoblast cells are not attacked by maternal effector cells is not yet known. There is a large group of CD_3 ~ - large granulocyte lymphocytes (LGL) in the decidua