论文部分内容阅读
[目的]观察应用枸橼酸莫沙比利治疗反流性食管炎的临床效果。[方法]将60例反流性食管炎患者分为观察组与对照组,每组30例。观察组患者服用枸橼酸莫沙比利,每次饭前5mg,3次/d;对照组患者服用多潘立酮,每次饭前10mg,3次/d。2组均加服用兰索拉唑,每次10mg,2次/d,早餐前和睡前服用,疗程为4周。2组在治疗前、后均进行了胃镜检查。[结果]观察组临床症状改善总有效率达93.33%,对照组达70.00%,2组总有效率比较,差异有统计学意义(P<0.05);胃镜检查提示观察组食管黏膜的改善情况明显好于对照组(P<0.05)。[结论]应用枸橼酸莫沙比利治疗反流性食管炎的疗效显著,使用安全。
[Objective] To observe the clinical effect of mosapride citrate in the treatment of reflux esophagitis. [Methods] 60 patients with reflux esophagitis were divided into observation group and control group, 30 cases in each group. Observation group patients taking mosapride citrate, 5mg each time before meals, 3 times / d; patients in the control group taking domperidone, each meal before 10mg, 3 times / d. 2 groups were treated with lansoprazole, each 10mg, 2 times / d, before breakfast and before going to bed, treatment for 4 weeks. Group 2 before and after treatment were gastroscopy. [Results] The total effective rate of clinical symptom improvement was 93.33% in the observation group and 70.00% in the control group. The total effective rate in the two groups was statistically significant (P <0.05). Gastroscopy showed that the improvement of esophageal mucosa in observation group was obvious Better than the control group (P <0.05). [Conclusion] Mosapride citrate treatment of reflux esophagitis significant effect, safe to use.