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目的分析沅陵县2005-2007年1 149例涂阳肺结核(TB)患者联合化疗转归情况,为进一步控制肺结核病的流行提供科学依据。方法对沅陵县2005-2007年1 149例涂阳肺结核患者的治疗情况进行统计学分析。病人诊断、治疗和管理严格按照《中国结核病防治规划实施工作指南》执行。结果2005-2007年沅陵县累计治管涂阳肺结核患者1149例,治愈1 053例,治愈率达91.6%。其中,初治涂阳治愈率为94.4%,复治涂阳治愈率为62.2%。初、复治涂阳病人治愈率差异有统计学意义(χ2=120.94,P<0.05),初、复治二组病人二月末痰菌阴转率,前者明显高于后者(χ2=38.38,P<0.05)。新发涂阳病人治愈率随年龄的增长而降低,各年龄组治愈率差异有统计学意义(χ2=17.46,P<0.05)。结论初治涂阳病人比复治涂阳病人化疗效果好,进一步加强归口管理,强化规则服药意识,提高病人发现率和诊治水平,是控制结核病流行的有效措施。
Objective To analyze the prognosis of 1 149 cases of smear positive pulmonary tuberculosis (TB) in Yuanling County from 2005 to 2007, and provide a scientific basis for further controlling the prevalence of pulmonary tuberculosis. Methods A total of 1 149 smear positive pulmonary tuberculosis patients in Yuanling County from 2005 to 2007 were analyzed statistically. Patient diagnosis, treatment and management in strict accordance with “China’s TB prevention and treatment planning implementation guidelines”. Results From 2005 to 2007, 1149 cases of smear positive pulmonary tuberculosis were treated in Yuanling County, and 1 053 cases were cured with a cure rate of 91.6%. Among them, the cure rate of newly diagnosed smear positive was 94.4%, the cure rate of retreated smear was 62.2%. The cure rate of smear positive patients and retreatment smear positive patients was statistically different (χ2 = 120.94, P <0.05). The sputum negative conversion rate in the two groups at the beginning and the end of retreatment was significantly higher than the latter (χ2 = 38.38, P <0.05). The cure rate of newly smear positive patients decreased with the increase of age, and the cure rate of each age group had significant difference (χ2 = 17.46, P <0.05). Conclusion The treatment of smear-positive patients is better than the smear-positive smear-positive patients. It is an effective measure to control the epidemic of tuberculosis by further strengthening the centralized management, strengthening the awareness of regular medication and improving the detection rate and diagnosis and treatment of patients.