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目的 探讨颅咽管瘤全切除患者术后发生低钠血症的诊断及处理方法。方法 回顾性分析我科近4年颅咽管瘤全切除术后并发低钠血症的36例患者。根据实验室检查、临床症状及中心静脉压确定低钠血症的类型并给予对症处理。结果1例死于继发性脑梗塞,1例自动出院,34例患者低钠血症状恢复。结论 中枢性低钠血症包括脑性盐耗综合征(CSWS)和抗利尿激素不适当分泌综合征(SIADH)。前者应予以充分补钠、补水,可通过肠内及静脉两种方式进行补充;后者却需要限水治疗。
Objective To investigate the diagnosis and treatment of hyponatremia after total resection of craniopharyngioma. Methods Retrospective analysis of 36 cases of hyponatremia complicated with craniopharyngioma resection in our department in recent 4 years. According to laboratory tests, clinical symptoms and central venous pressure to determine the type of hyponatremia and given symptomatic treatment. Results One patient died of secondary cerebral infarction and one patient was discharged spontaneously. The hyponatremia symptoms of 34 patients recovered. Conclusions Central hyponatremia includes cerebrospinal fluid syndrome (CSWS) and antidiuretic hormone inappropriate secretion syndrome (SIADH). The former should be fully sodium supplementation, replenishment, by enteral and intravenous two ways to supplement; the latter need water treatment.