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近20年间,日本的慢性肝病、肝硬化及肝癌,尤其男性有增加倾向,成为男性主要死因之一。肝细胞癌的80%合并肝硬化和肝纤维化,因此认为肝硬化是一种癌前状态。可是欧美各国肝癌极少发生,因为欧美多为酒精性肝硬化,而日本多为病毒性肝硬化,不过,近年来日本的酒精性肝硬化也在不断增加。病毒性肝硬化、酒精性肝硬化和肝癌关系如何?有进一步研究的必要。日本东大第一内科1974年4月～1982年12月收治肝硬化和肝硬化合并肝癌患者238例,行HBs抗原检查,肝硬化的75%为病毒性的,20%为酒精性的,5%为
In the past 20 years, Japan’s chronic liver disease, cirrhosis and liver cancer, especially men, have an increasing propensity to become one of the major causes of death in men. Eighty percent of hepatocellular carcinoma has cirrhosis and fibrosis, and therefore cirrhosis is considered a precancerous condition. However, liver and cancer in Europe and the United States rarely occur, because Europe and the United States are mostly alcoholic cirrhosis, and Japan is mostly viral cirrhosis, however, in recent years Japan’s alcoholic cirrhosis is also increasing. Viral cirrhosis, alcoholic cirrhosis and liver cancer how? There is a need for further research. Japan’s National Departments of Internal Medicine from April 1974 to December 1982 admitted to liver cirrhosis and cirrhosis in 238 patients with liver cancer, HBs antigen test, 75% of cirrhosis is viral, 20% alcoholic, 5 %for