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目的:探讨早产孕妇母血C-反应蛋白(CRP)水平与早产胎膜早破和亚临床绒毛膜羊膜炎的关系。方法:选取2011年10月~2012年10月银川市第一人民医院96例早产孕妇,采取散射比浊法检测血清CRP水平并进行统计学分析。结果:早产孕妇中胎膜早破者和亚临床绒毛膜羊膜炎者血清CRP水平分别为(12.03±2.87)mg/L和(14.76±2.64)mg/L,均显著高于无胎膜早破组的(3.89±1.92)mg/L和无亚临床绒毛膜羊膜炎组的(3.23±1.03)mg/L(P<0.05)。结论:C-反应蛋白浓度变化在检测早产孕妇胎膜早破和亚临床绒毛羊膜炎具有较好的临床价值,可用于临床早期诊断。
Objective: To investigate the relationship between maternal serum C-reactive protein (CRP) and preterm premature rupture of membranes and subclinical chorioamnionitis in preterm labor. Methods: From October 2011 to October 2012, 96 pregnant women with preterm birth in First People’s Hospital of Yinchuan City were selected for detection of serum CRP level by statistical method. Results: The serum levels of CRP in premature rupture of membranes and subclinical chorioamnionitis were (12.03 ± 2.87) mg / L and (14.76 ± 2.64) mg / L respectively, both significantly higher than those without premature rupture of membranes (3.89 ± 1.92) mg / L in the control group and (3.23 ± 1.03) mg / L in the subclinical chorioamnionitis group (P <0.05). Conclusion: The change of C-reactive protein has a good clinical value in the detection of premature rupture of membranes and subclinical chorioamnionitis, which can be used for early clinical diagnosis.