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目的:探讨应用黄连素片联合克拉霉素进行幽门螺旋杆菌感染慢性胃炎治疗的临床疗效。方法:选取到我院进行治疗并确诊为幽门螺旋杆菌慢性胃炎的80例患者为研究对象,并随机分为对照组和观察组,分别给予单一服用克拉霉素、黄连素片联合克拉霉素同时服用的治疗方式,分析和评价两组患者治疗14d后的总有效率及临床症状改善情况。结果:观察组患者治疗后的总有效率与对照组相比,差异显著(P<0.05);观察组患者的胃胀、胃痛、嗳气、反酸等临床症状改善情况较之对照组明显较优,两组差异具有统计学意义(P<0.05)。结论:在对幽门螺旋杆菌慢性胃炎患者的治疗过程中,采用黄连素片联合克拉霉素的治疗方式,治疗效果确切,能明显改善患者的临床症状。
Objective: To investigate the clinical efficacy of berberine tablets combined with clarithromycin in the treatment of chronic gastritis with Helicobacter pylori infection. Methods: Eighty patients with chronic gastritis diagnosed as Helicobacter pylori in our hospital were enrolled in the study. They were randomly divided into control group and observation group. Patients were given single clarithromycin, berberine and clarithromycin simultaneously Taking the treatment, analysis and evaluation of the two groups of patients after treatment 14d total effective rate and improvement of clinical symptoms. Results: The total effective rate in observation group was significantly higher than that in control group (P <0.05). The improvement of clinical symptoms such as bloating, stomachache, belching and acid reflux in observation group was better than that in control group , The difference between the two groups was statistically significant (P <0.05). Conclusion: In the treatment of patients with Helicobacter pylori chronic gastritis, the treatment of berberine combined with clarithromycin, the exact effect, can significantly improve the clinical symptoms of patients.