论文部分内容阅读
目的调查2011~2012年四川大学华西医院健康体检人群亚临床甲状腺功能减退症(简称亚甲减)的患病情况,并探讨性别与甲减和代谢综合征(MS)的关系。方法对2011~2012年在四川大学华西医院进行健康体检并行甲状腺功能检测的人群进行调查。其内容包括采集患者的病史、血压、身高、体重、甲状腺功能、空腹血糖、甘油三酯和高密度脂蛋白胆固醇等。统计分析采用SPSS 18.0软件。结果共纳入11?976名接受了甲状腺功能检测者,其中男性7?488人,女性4?488人。该11?976名体检人群中共发现亚甲减患者1?820例,占15.20%。其中男性884例(患病率11.81%),女性936例(患病率20.86%),女性患病率明显高于男性(P<0.01)。60岁以上人群的患病率高于其他年龄段。共发现MS患者1?145例,其中男性1?005例(患病率13.42%),女性140例(患病率3.12%),男性患病率明显高于女性(P<0.01)。MS组的亚甲减患病率最高,正常代谢组的患病率最低(P<0.01)。MS组的TSH水平最高,正常代谢组最低(P<0.01)。结论健康体检人群中亚甲减患病率较高,且亚甲减患者发生MS的可能性明显增高。
Objective To investigate the prevalence of subclinical hypothyroidism in Huaxi Hospital of Sichuan University from 2011 to 2012 and to explore the relationship between sex and hypothyroidism and metabolic syndrome (MS). Methods From 2011 to 2012, Huaxi Hospital of Sichuan University conducted a survey of concurrent thyroid function tests in healthy people. Its contents include collecting the patient’s medical history, blood pressure, height, weight, thyroid function, fasting blood glucose, triglycerides and high-density lipoprotein cholesterol. Statistical analysis using SPSS 18.0 software. Results A total of 11 to 976 patients who had thyroid function tests were enrolled, of whom 7 to 488 males and 4 to 488 females. A total of 1 820 cases of methylenemia were found in 11-976 medical examination population, accounting for 15.20%. There were 884 males (prevalence rate 11.81%) and 936 females (prevalence rate 20.86%). The prevalence of females was significantly higher than that of males (P <0.01). The prevalence of people over the age of 60 is higher than other age groups. A total of 1 145 MS patients were found, among which 1 005 were male (prevalence rate was 13.42%) and 140 were women (prevalence was 3.12%). The prevalence of male was significantly higher than that of female (P <0.01). Methylmethionine had the highest prevalence in MS group and the lowest in normal metabolite group (P <0.01). The highest level of TSH was found in MS group, the lowest in normal group (P <0.01). Conclusions The prevalence of hypothyroidism is higher in the health examination population, and the possibility of MS in patients with methylenetetrazole reduction is significantly higher.