1前言青霉素的发明,成功地治疗了临床上金黄色葡萄球菌感染的问题。随后问世的各种抗生素使得细菌性感染死亡率大为降低,多种抗生素在应用多年后,出现了耐药菌,它对药物的敏感性小,致使药物疗效降低甚至无效,导致此问题的主要原因是抗生素滥用。耐药菌问题引起的医院内感染人数,已占住院感染 1 Introduction The invention of penicillin has successfully treated the clinical problem of Staphylococcus aureus infection. After the advent of a variety of antibiotics make bacterial infection greatly reduced mortality, many kinds of antibiotics after many years of application, the emergence of drug-resistant bacteria, its drug sensitivity is small, resulting in reduced or even ineffective drug, leading to the main problem The reason is abuse of antibiotics. The number of hospital infections caused by drug-resistant bacteria has accounted for hospital infection