巨细胞病毒感染是世界上最常见的先天性感染,在新生儿中的发生率为0.2％～2.2％。10％产前感染的新生儿在出生时就有症状:20％死亡,幸存者中90％出现远期后遗症,因此产巨细胞感染的诊断和预防是围生期学的重要课题。为了解初次巨细胞病毒感染并存在垂直传播的母儿妊娠结局,选取1992～2000年50例确诊初次感染巨细胞病毒并存在垂直传 Cytomegalovirus infection is the most common congenital infection in the world, with a neonatal incidence of 0.2% to 2.2%. Ten percent of prenatal infections of newborns have symptoms at birth: 20% of deaths, 90% of survivors have long-term sequelae, so the diagnosis and prevention of giant cell infection is an important issue in perinatal science. In order to understand the initial cytomegalovirus infection and the vertical transmission of pregnant women and children with the outcome of pregnancy, selected 50 cases from 1992 to 2000 confirmed the initial infection of cytomegalovirus and the existence of vertical transmission