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The blade number of impeller is an important design parameter of pumps,which affects the characteristics of pump heavily.At present,the investigation focuses mostly on the performance characteristics of axis flow pumps,the influence of blade number on inner flow filed and characteristics of centrifugal pump has not been understood completely.Therefore,the methods of numerical simulation and experimental verification are used to investigate the effects of blade number on flow field and characteristics of a centrifugal pump.The model pump has a design specific speed of 92.7 and an impeller with 5 blades.The blade number is varied to 4,6,7 with the casing and other geometric parameters keep constant.The inner flow fields and characteristics of the centrifugal pumps with different blade number are simulated and predicted in non-cavitation and cavitation conditions by using commercial code FLUENT.The impellers with different blade number are made by using rapid prototyping,and their characteristics are tested in an open loop.The comparison between prediction values and experimental results indicates that the prediction results are satisfied.The maximum discrepancy of prediction results for head,efficiency and required net positive suction head are 4.83％,3.9％ and 0.36 m,respectively.The flow analysis displays that blade number change has an important effect on the area of low pressure region behind the blade inlet and jet-wake structure in impellers.With the increase of blade number,the head of the model pumps increases too,the variable regulation of efficiency and cavitation characteristics are complicated,but there are optimum values of blade number for each one.The research results are helpful for hydraulic design of centrifugal pump.