国产涤纶片与进口硬脑膜片对幼兔巩膜影响的实验研究

来源 :中国医科大学学报 | 被引量 : 0次 | 上传用户:loserlu
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目的 :对比国产涤纶片与进口硬脑膜片在后巩膜加固术中的作用。方法 :选 1月龄幼兔 18只 ,采用 Nur-mamedov NN术式 ,手术前后观察眼部情况 ,眼压 ,眼轴变化。结果 :术后不同时期两组眼轴长度差异不显著 (经 t检验 ,P >0 .0 5 ) ,术后眼压与术前差异不显著 (经 t检验 ,P >0 .0 5 ) ,病理观察发现实验组比对照组炎性反应明显 ,新生血管和成纤维细胞丰富 ,并长入植片间隙内 ,两组新生血管累计平均数差异非常显著 (经 t检验 ,P <0 .0 1) ,未发现严重并发症及不良反应。结论 :国产涤纶片生物相容性好可以作为后巩膜加固术的材料。 Objective : To compare the effects of domestic polyester sheets and imported dura mater in posterior scleral reinforcement. METHODS: Eighteen 1-month-old rabbits were selected and Nur-mamedov NN was used. The eye condition, intraocular pressure, and axial changes were observed before and after surgery. RESULTS: There was no significant difference in axial length between the two groups at different postoperative periods (P>0.05). Postoperative intraocular pressure was not significantly different from preoperative ones (P>0.05). Pathological observations revealed that the experimental group had significantly more inflammatory responses than the control group, with rich neovascularization and fibroblasts, and grew into the interstitial space. There was a significant difference in cumulative mean neovascularization between the two groups (t-test, P < 0.01). No serious complications or adverse reactions were found. Conclusion: The biocompatibility of homemade polyester sheet can be used as material for posterior scleral reinforcement.
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