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目的探讨综合治疗方法对牙周-牙髓联合病变临床治疗的效果。方法选取我诊所2010年9月~2014年3月经诊断为牙周-牙髓联合病变的患者126例，共有患牙148颗，根据具体情况，制定综合治疗方案，在1年后，根据不同牙位及不同类型的牙周-牙髓联合病变患牙进行疗效比较。结果联合治疗总有效率84.5%，其中根尖周病变引起的牙周病变治疗效果好，且前牙好于前磨牙好于后磨牙。结论牙周牙髓联合病变者采取综合治疗，能够取得良好的效果，值得临床推荐。“,”Objective Study the treatment method of combined periodontic-endodontic; lesions and explore the best treatment proce-dure. Methods In 2010 September ~2014 year selected in our clinic during March diagnosed 126 cases of combined periodontic endodontic lesion of patients, a total of 148 teeth, according to the specific situation. Results Combined treatment of the total ef iciency of 84.5%, which caused by the lesion of periodontal treatment ef ect of periapical lesions, and anterior teeth bet er than premolars were bet er than the molar . Conclusion Combined treatment of combined periodontic-endododontic lesions can achieve good ef ect and can preserve the teeth bet er.