继Malling(1971)和Ames之后,目前,已有不少化学致癌物短期试验系统采用哺乳动物肝S9对前致癌物、前致突变物作体外代谢活化。所谓S9,即为富含微粒体的组织匀浆9000克上清液。而其中主要有效成份是附着在微粒体膜上的混 Following the Malling (1971) and Ames, at present, many short-term chemical carcinogens test system using mammalian liver S9 for pre-carcinogens, pre-mutants in vitro metabolic activation. The so-called S9, which is rich in microsomal tissue homogenate 9000 grams of supernatant. Which is the main active ingredient is attached to the microsomal membrane mixed