肺神经内分泌细胞位于气道上皮层内 ,可分泌活性胺和肽类激素 ,兼有神经细胞及内分泌细胞的特征。已证实肺神经内分泌细胞能作为气道感受器 ,具有促进肺的发育以及调节气道反应性等生理功能。肺神经内分泌细胞也参与了肺癌、肺囊性纤维化等多种肺疾病的发生、发展过程 ,并可通过多种途径促进肺损伤修复 Pulmonary neuroendocrine cells located in the airway epithelium can secrete active amines and peptide hormones, both neuronal and endocrine cells. It has been demonstrated that pulmonary neuroendocrine cells act as airway receptors and have physiological functions such as promoting lung development and regulating airway responsiveness. Pulmonary neuroendocrine cells are also involved in the occurrence and development of many lung diseases such as lung cancer and cystic fibrosis, and can promote the repair of lung injury through various ways