性能优良的光学探针是构建高灵敏度、高时空分辨能力的光学传感与活体成像分析方法的物质基础,其发展一直受到人们的关注。中国科学院化学研究所活体分析化学实验室马会民课题组长期从事该方面的研究,并取得了一系列成果。酪氨酸酶是黑色素癌的重要标志物,并与白化病、帕金森等疾病密切相关,因此发展酪氨酸酶的光学传感与成像分 Optical probe with excellent performance is the material foundation for constructing optical sensing and living body imaging analysis method with high sensitivity and high spatiotemporal resolving power. Its development has been attracting much attention. Chinese Academy of Sciences Institute of Chemistry in vivo analytical chemistry laboratory Ma Huimin group has long been engaged in research in this area and has made a series of achievements. Tyrosinase is an important marker of melanoma and is closely related to diseases such as albinism and Parkinson’s disease. Therefore, the development of tyrosinase optical sensing and imaging