细胞凋亡在正常组织器官的发育及机体自身稳定中起着生理性细胞清除作用,是生物体维持自身稳定的重要负调节机制。子宫内膜功能层细胞的清除依赖于月经周期的分泌晚期及月经期的细胞凋亡作用,以用来保持子宫内膜的周期性更新。子宫内膜异位症(EMs)患者的在位、异位内膜与非EMs患者的正常子宫内膜相比,在由Bcl-2家族和Fas/FasL系统介导的细胞凋亡机制上有着明显的不同,这有助于子宫内膜细胞在腹腔的异位种植以及EMs病情的发展。 Apoptosis plays a role of physiological cell scavenging in the development of normal tissues and organs and its own stability, which is an important negative regulation mechanism of the organism to maintain its own stability. Endometrial clearance of functional layer cells depends on the menstrual cycle of late secretion and menstrual apoptosis, in order to maintain the cyclical update of the endometrium. The eutopic and ectopic endometrium of patients with endometriosis (EMs) has a mechanism of apoptosis mediated by the Bcl-2 family and the Fas / FasL system as compared with the normal endometrium of non-EMs patients Significantly different, which contributes to the ectopic implantation of endometrial cells in the abdominal cavity and the development of EMs disease.