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目的探讨儿童清洁手术预防性应用抗菌药物的合理性。方法对某院2011年11月-2012年8月出院的清洁手术患儿的用药情况进行调查、分析。结果 790例病例中,抗菌药物预防性使用率达34.4%;采用术前0.5~2 h给药者219例,占80.5%;术后抗菌药物平均使用3.7 d;预防性应用抗菌药物涉及5类13种,其中头孢菌素类235例居首位。结论该院儿科清洁手术围手术期抗菌药物应用存在用药指征把关不严、用药品种选择、给药时机及用法用量不当等问题,尚待进一步规范管理。
Objective To explore the rationality of prophylactic use of antibacterials in children’s clean operation. Methods A hospital from November 2011 to August 2012 were discharged from the clean operation of children were investigated and analyzed. Results Among 790 cases, the prophylactic use rate of antimicrobial agents was 34.4%; 219 cases (80.5%) were given 0.5 ~ 2 h before surgery; the average duration of antimicrobial agents was 3.7 days; and the prophylactic use of antimicrobial agents was related to 5 categories 13 species, of which 235 cases of cephalosporins ranks first. Conclusions There are some problems in the perioperative antibacterial application of pediatric cleansing surgery, such as lax indications, improper medication selection, timing of administration and improper usage of dosage.