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目的总结胼胝体压部(SCC)可逆性孤立性病变的MRI、~1H-MRS特点,初步研究病灶持续存在时间与表观扩散系数(ADC)值的相关性。方法回顾性分析15例SCC可逆性孤立性病变患者的临床及影像表现,探讨SCC病灶持续时间与年龄、最大横截面积、ADC值的相关关系,以病灶持续时间为因变量(Y),年龄(X_1)、最大横截面积(X_2)、ADC值(X_3)为自变量,进行逐步回归分析,求出多元线性回归模型。结果病灶位于SCC中线区,单发,边界清楚,呈等/长T_1、长T_2信号,T_2-FLAIR及DWI序列呈高信号,ADC图低信号,增强后无强化,平均经过18.4天后消失。MRS均未见明显异常表现。ADC值与病灶持续时间呈中度正相关(r=0.624,P<0.05),病灶持续时间的影响因素包括最大横截面积和ADC值(R~2=0.618,F=2.924,P=0.012),多元逐步回归分析结果显示,ADC值对病灶持续时间有正向预测作用(R~2=0.389,F=8.277,P=0.013)。结论 SCC可逆性孤立性病变的MRI表现具有明显的特征性,对其明确诊断具有重要意义,并可根据其ADC值初步推测病灶持续存在的时间。
Objective To summarize the MRI and 1H-MRS features of invertible solitary lesions of the corpus callosum (SCC), and to study the relationship between the persistence of lesions and apparent diffusion coefficient (ADC) values. Methods The clinical and imaging findings of 15 cases of solitary solitary lesions with SCC were retrospectively analyzed. The relationship between duration of SCC lesions and age, maximum cross-sectional area and ADC value was analyzed. The duration of lesions as the dependent variable (Y), age (X_1), maximum cross-sectional area (X_2) and ADC value (X_3) were independent variables. The multiple linear regression model was obtained by stepwise regression analysis. Results The lesion was located in the midline of SCC. The lesions were clear with single / long T_1, long T_2, T_2-FLAIR and DWI sequences. The ADC showed low signal and no enhancement after enhancement. The average disappeared after 18.4 days. MRS showed no obvious abnormalities. There was a moderate positive correlation between the ADC value and the duration of the lesion (r = 0.624, P <0.05). The influencing factors of the lesion duration included the maximum cross-sectional area and ADC value (R 2 = 0.618, F = 2.924, P = 0.012) The results of multivariate stepwise regression analysis showed that ADC value had a positive predictive value for the duration of the lesion (R ~ 2 = 0.389, F = 8.277, P = 0.013). Conclusion The MRI manifestations of solitary solitary lesions of SCC have obvious characteristics, which are of great significance for its definite diagnosis. The duration of persistent lesions can be preliminarily estimated based on the ADC values.