原发免疫性血小板减少症(ITP)是一种常见的出血性疾病,其发病机制仍不十分清楚。现有治疗方案在ITP的治疗中取得一定的疗效,如糖皮质激素、静脉注射免疫球蛋白以及脾切除等,但仍有较多患者面临复发难治的问题。现将近年ITP发病机制、诊断和治疗等方面的研究进展作一综述。 Primary immune thrombocytopenia (ITP) is a common hemorrhagic disease, the pathogenesis is still not very clear. Existing therapies have achieved certain therapeutic effects in the treatment of ITP, such as glucocorticoid, intravenous immunoglobulin and splenectomy, but more patients are still facing the problem of refractory relapse. Now in recent years ITP pathogenesis, diagnosis and treatment of research progress are reviewed.