骨髓炎是伤寒和甲型副伤寒的罕见并发症。作者首次报告了应用甲氧苄胺嘧啶—磺胺甲基异恶唑(TMP-SMZ)治愈一例副伤寒甲沙门氏菌骨髓炎。患者系农民,16岁,因右肩关节活动时严重疼痛伴发热、乏力和排尿困难而入院。入院前已反复发热一年多,每次发热常持续1～2周。在第一次发热约6个月后出现右肩肿痛。体格检查:面色苍白,体温38℃,右肩活动障碍。右肱骨上端呈梭形 Osteomyelitis is a rare complication of typhoid and paratyphoid. The authors first reported the use of trimethoprim-sulfamethoxazole (TMP-SMZ) to cure one paratyphoid A salmonellosis osteomyelitis. The patient, a peasant, was 16 years old and was admitted to hospital for severe pain associated with fever, weakness and dysuria on his right shoulder. Pre-admission fever has been repeated more than a year, each fever often last 1 to 2 weeks. Right shoulder swelling and pain occurred about 6 months after the first fever. Physical examination: pale, temperature 38 ℃, right shoulder activity disorders. Right upper humerus spindle