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在我们以往的实验中,已经证实系统性红斑狼疮患者的染色体结构畸变率显著高于健康人者,但受检的患者中多数处于接受醋酸强的松治疗阶段或于近期内接受过醋酸强的松治疗。醋酸强的松作为免疫抑制剂,有抑制T淋巴细胞分裂的作用,但能否引起染色体结构畸变尚未见有报导。为了排除醋酸强的松对系统性红斑狠疮患者的致染色体结构畸变作用,我们进行了本实验。材料和方法随机选取健康成年家兔7只,雌雄兼
In our previous experiments, it has been confirmed that the chromosome structural aberration rate of patients with systemic lupus erythematosus is significantly higher than that of healthy individuals, but most of the patients examined are in the stage of prednisone treatment or have received strong acetic acid in the near future. Loosening treatment. Prednisone acetate acts as an immunosuppressant and inhibits the division of T lymphocytes. However, it has not been reported whether chromosome structural aberrations can be caused. In order to exclude the effects of prednisone acetate on chromosome structural aberrations in patients with systemic rosacea, we performed this experiment. Materials and Methods 7 healthy adult rabbits were selected at random, male and female