目的　探讨盐酸氨溴索治疗新生儿感染性肺炎的疗效和安全性。方法　以 2 0 0 1年 1～ 5月住院的新生儿感染性肺炎 4 6例为对照组 ,2 0 0 2年 1～ 5月住院的新生儿感染性肺炎 39例为治疗组。两组均采用常规治疗。治疗组加用盐酸氨溴索 (1mg/kg ,po ,tid)治疗。 结果　治疗组肺部罗音消失天数、住院天数、需人工吸痰次数均较对照组显著减少 (P <0 0 1)。观察过程中未发现与氨溴索相关的药物不良反应。结论　盐酸氨溴索治疗新生儿感染性肺炎具有显著的疗效和较好的安全性。 Objective To investigate the efficacy and safety of ambroxol hydrochloride in the treatment of neonatal pneumonia. Methods From January to May in 2001, 46 neonates with infectious pneumonia were hospitalized in the control group. From January to May in 2002, 39 neonates with infectious pneumonia were treated in the treatment group. Both groups were treated routinely. Treatment group plus ambroxol hydrochloride (1mg / kg, po, tid) treatment. Results In the treatment group, the days of disappearance of pulmonary rales, days of hospitalization, and the number of manual sputum aspiration were significantly decreased (P <0.01). No adverse reactions to ambroxol were observed during the observation. Conclusion Ambroxol Hydrochloride for neonatal pneumonia has significant efficacy and good safety.