轮状病毒肠炎是秋冬季婴幼儿腹泻的常见病,约占我国婴幼儿腹泻病因的40%[1-2]。由于传染性强,发病率高,目前尚无特殊治疗,临床常规治疗为肠黏膜保护剂、微生态调节剂和液体疗法,但疗效并不理想。近年来各地医院在以上综合治疗基础上加用重组人干扰素α1b取得一定疗效[3-5],但是由于采用肌肉注射 Rotavirus enteritis is a common disease of infants with diarrhea in autumn and winter, accounting for about 40% of the etiology of infantile diarrhea in China [1-2]. Due to its high contagiousness and high incidence, no special treatment is available at present. The conventional clinical treatment is intestinal mucosal protective agent, micro-ecological regulator and liquid therapy, but the curative effect is not satisfactory. In recent years, hospitals around the above comprehensive treatment based on the use of recombinant human interferon α1b achieved a certain effect [3-5], but due to the use of intramuscular