骨巨细胞瘤是一种潜在恶性和易复发的骨肿瘤，膝关节是骨巨细胞瘤的好发部位，50％发生在股骨下端和胜骨上端。目前治疗仍以手术为主。手术方式的选择依据肿瘤的分级，组织浸润扩散的程度，骨肿瘤骨壳是否完整及是否反复发作有恶变而不同，可分为刮除、灭活、植骨、瘤段切除、 Giant cell tumor of bone is a potentially malignant and recurring bone tumor. The knee joint is a predilection site for giant cell tumor of bone, and 50% occurs at the lower end of the femur and the upper end of the sacrum. The current treatment is still based on surgery. The choice of surgical methods depends on the grade of the tumor, the degree of tissue infiltration and spread, whether the bone tumor is complete and whether it is malignant or recurrent. It can be divided into scraping, inactivation, bone grafting, and tumor resection.