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目的观察左卡尼汀联合低温血液透析对透析相关性低血压的疗效。方法选择本院透析中发生低血压发生患者48例,随机分为空白对照,低温血液透析(对照组)及应用左卡尼汀联合低温血液透析3种方式治疗,通过比较血液透析血压的变化,观察3组透析前、透析中、透析后低血压发生率和不良反应。结果三组患者透析间期体重增加量和实际超滤量差异无统计学意义(P>0.05),治疗组血液透析过程低血压发生显著低于对照组(P<0.05)。结论左卡尼汀联合低温血液透析对透析相关性低血压疗效好,无不良反应,值得推广应用。
Objective To observe the effect of levocarnitine combined with hypothermia hemodialysis on dialysis-related hypotension. Methods Forty-eight patients with hypotension occurred during dialysis were randomly divided into blank control, hypothermia hemodialysis (control group) and levocarnitine plus hypothermia hemodialysis. By comparing the changes of hemodialysis blood pressure, 3 groups before dialysis, dialysis, the incidence of post-dialysis hypotension and adverse reactions. Results There was no significant difference between the three groups in weight gain and actual ultrafiltration volume during dialysis (P> 0.05). The incidence of hypotension during hemodialysis in treatment group was significantly lower than that in control group (P <0.05). Conclusion L-carnitine combined with hypothermia hemodialysis dialysis-related hypotension with good efficacy, no adverse reactions, it is worth promoting the application.