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目的:观察、对比泮托拉唑和奥美拉唑治疗胃溃疡的疗效,为临床实践提供参考与指导。方法:将88例胃溃疡患者作为临床研究对象,分设泮托拉唑治疗组与奥美拉唑治疗组,每组随机分配患者44例,在常规治疗的基础上,根据分组分别予以对应药物进行治疗。结果:两组患者的治疗总有效率和不良反应发生率基本保持一致,但与奥美拉唑治疗组相比,泮托拉唑治疗组的幽门螺旋杆菌根除率显著更高,6个月内的复发率也明显更低。结论:在胃溃疡的治疗上,泮托拉唑与奥美拉唑相比,能够进一步提高幽门螺旋杆菌的根除率,并降低胃溃疡的发病率,具有临床推广价值。
Objective: To observe and compare the efficacy of pantoprazole and omeprazole in the treatment of gastric ulcer, and provide reference and guidance for clinical practice. Methods: 88 cases of gastric ulcer patients as clinical research object, divided into pantoprazole treatment group and omeprazole treatment group, 44 patients were randomly assigned to each group, on the basis of routine treatment, according to the group were given corresponding drugs treatment. Results: The total effective rate and the incidence of adverse reactions in both groups were basically the same, but compared with omeprazole group, pantoprazole eradication rate was significantly higher in H. pylori group, within 6 months The recurrence rate was also significantly lower. Conclusion: In the treatment of gastric ulcer, pantoprazole compared with omeprazole, can further improve the eradication rate of Helicobacter pylori and reduce the incidence of gastric ulcer, with clinical value.