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采用阿苯达唑400mg/d×3d、400mg/d×5d和噻嘧啶1500mg/d×3d、1500mg/d×5d治疗肠道线虫感染者720例。治后半月检查,钩虫卵阴转率分别为98.6、98.6、86.2和93.5％;蛔虫卵阴转率分别为96.5、98.2、92.9和96.3％;鞭虫卵阴转率分别为86.4、89.0、68.9和67.0％。钩虫卵减少率均在98.0％以上。治后半年复查,各组钩虫阳性率均有不同程度回升,虫种由治前美洲钩虫为主,转为十二指肠钩虫为主。结果显示,回升的原因主要是十二指肠钩虫引起,而阿苯达唑400mg/d×3d和400ms/d×5d控制钩虫感染回升有明显作用。
720 cases of intestinal nematode infection were treated with albendazole 400mg / d × 3d, 400mg / d × 5d and pyrantel 1500mg / d × 3d, 1500mg / d × 5d. After half a month of treatment, the negative conversion rates of hookworm eggs were 98.6, 98.6, 86.2 and 93.5% respectively; the negative conversion rates of Ascaris eggs were 96.5, 98.2, 92.9 and 96.3%, respectively; the egg negative conversion rates of whipworm eggs were 86.4, 89.0, 68.9 and 67.0%. Hook worm eggs reduce the rate of more than 98.0%. After six months of re-examination, the positive rate of hookworm in each group had a different degree of recovery, insects species prevalent by the hookworm prevalent, into the main hookworm duodenal. The results showed that the main reason for the rebound caused by hookworm duodenal, and albendazole 400mg / d × 3d and 400ms / d × 5d control hookworm infection picked up a significant role.