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尿酸是嘌呤代谢的产物,作为一种内源性抗氧化剂,在CNS炎症性脱髓鞘病的病理损害过程中有保护作用。多发性硬化(MS)患者的血清尿酸水平低于其他神经系统疾病患者,处于MS急性期患者的血清尿酸水平低于非急性期患者。血清尿酸水平的动态检测有助于MS复发与缓解的判断。该文就此进行综述。
Uric acid is a product of purine metabolism, as an endogenous antioxidant that has a protective role in the pathological damage of CNS inflammatory demyelinating disease. Serum uric acid levels are lower in patients with multiple sclerosis (MS) than in other neurological diseases, and patients with MS in the acute phase have lower serum uric acid levels than non-acute patients. Dynamic detection of serum uric acid levels can help determine MS relapse and remission. This article reviews this.