目的探讨立体定向靶向注射尿激酶治疗脑室出血铸型的疗效。方法采用立体定向靶向穿刺单侧或双侧脑室,后予以脑室内注射尿激酶行纤溶治疗,拔管后联合腰大池持续引流,预后采用ADL评定。结果全部未见颅内感染及再出血等并发症,ADLⅠ级2例,ADLⅡ级8例,ADLⅢ级8例,ADLⅣ级4例,ADLⅤ级2例,自动出院2例。结论立体定向靶向脑室内注射尿激酶治疗脑室出血铸型是挽救生命的一种重要方法,其方法安全、有效。 Objective To investigate the efficacy of stereotactic targeted injection of urokinase in the treatment of intraventricular hemorrhage. Methods Stereotactic targeted puncture of unilateral or bilateral ventricle, intrauterine injection of urokinase after fibrinolysis treatment, drainage combined with continuous lumbar cistern drainage, the prognosis of ADL assessment. Results No complications such as intracranial infection and rebleeding were found. There were 2 cases of ADLⅠ, 8 cases of ADLⅡ, 8 cases of ADLⅢ, 4 cases of ADL Ⅳ and 2 cases of ADLⅤ. Conclusion Stereotactic targeting of intracerebroventricular injection of urokinase in the treatment of intraventricular hemorrhage is an important method of saving lives, its method is safe and effective.