Safety analysis for liquid rocket engine has a great meaning for shortening development cycle, saving development expenditure and reducing development risk. The relationship between the structure and component of liquid rocket engine is much more complex, furthermore test data are absent in development phase. Thereby, the uncertainties exist in safety analysis for liquid rocket engine. A safety analysis model integrated with FMEA(failure mode and effect analysis)based on Bayesian networks (BN) is brought forward for liquid rocket engine, which can combine qualitative analysis with quantitative decision. The method has the advantages of fusing multi-information, saving sample amount and having high veracity. An example shows that the method is efficient.