对肝脏病引起内分泌紊乱的认识逐步深化,本文着重从内分泌激素改变方面进行概述。 胰岛素 糖尿病在普通人群发病率约1～2％,在慢性肝病患者可达32％,糖耐量降低者可达80％。这种“肝源性糖尿病”具有高胰岛素血症和胰岛素对葡萄糖负荷的反应减弱等特点。Proietto等曾报告一组肝硬化病例,血浆胰岛素水平比正常高2倍,糖代谢清除率 Understanding of endocrine disorders caused by liver disease gradually deepened, this article focuses on the overview of changes in endocrine hormones. Insulin diabetes in the general population incidence of about 1 to 2% in patients with chronic liver disease up to 32%, impaired glucose tolerance up to 80%. This “liver-derived diabetes” is characterized by hyperinsulinemia and a diminished insulin response to glucose load. Proietto et al have reported a group of cirrhosis cases, plasma insulin levels 2 times higher than normal, glucose metabolism clearance