目的对比重型颅脑创伤(TBI)术后持续或间断腰大池脑脊液引流的应用效果。方法选取2015年1月—11月我院收治的86例TBI患者,将其中40例采用常规腰穿脑脊液间断排放的患者设为对照组,将46例腰大池持续脑脊液引流的患者设为观察组,对比分析2组应用效果。结果对照组颅内压正常时间、头痛持续时间、脑脊液红细胞廓清时间均明显长于观察组,差异显著(P<0.05);观察组治疗效果明显优于对照组、脑积水发生率明显低于对照组,差异显著(P<0.05)。结论重型颅脑创伤术后实施腰大池持续脑脊液引流效果显著,有利于改善患者临床症状,减少术后并发症,值得临床推广应用。 Objective To compare the effect of continuous or intermittent lumbar cisterna cerebrospinal fluid drainage after severe traumatic brain injury (TBI). Methods Totally 86 patients with TBI who were treated in our hospital from January to November 2015 were enrolled and 40 patients with intermittent discharge of cerebrospinal fluid by routine lumbar puncture were selected as the control group. 46 patients with continuous drainage of cerebrospinal fluid , Comparative analysis of two groups of application results. Results The time of normal intracranial pressure, the duration of headache and the clearance time of cerebrospinal fluid erythrocytes in the control group were significantly longer than those in the observation group (P <0.05). The treatment group in the observation group was significantly better than the control group, and the incidence of hydrocephalus was significantly lower than that in the control group Group, the difference was significant (P <0.05). Conclusion The implementation of continuous lumbar cistern with cerebrospinal fluid drainage in patients with severe craniocerebral trauma is effective in improving clinical symptoms and reducing postoperative complications and is worthy of clinical application.