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中毒性流行性综合征(Toxic Epidemic Syndrome,TES)是1981年开始在西班牙流行的一种多系统损害的新病种。在流行期(1981年5月~1982年末)约有2万余人罹患,350人以上死亡,至今仍留下一定数量的慢性期残疾病人。本病由Tabuenca首先报告,称为中毒过敏性综合征。流行病学调查的结果证实TES的发病与摄入变质后经处理过的菜油有关,故又称为“西班牙中毒性油综合征”。本病虽未见于国内,但病因未最后明确,不能保证今后不再流行,且大部份患者均有皮肤损害,故综合部份文献,介绍如下。
Toxic Epidemic Syndrome (TES) is a new kind of multi-system damage that started in Spain in 1981. In the prevalent period (from May 1981 to the end of 1982) about 2 million people were suffering from more than 350 deaths, still leaving a certain number of chronic disability patients. The disease was first reported by Tabuenca, known as anaphylactoid syndrome. Epidemiological survey results confirmed that the incidence of TES and intake of deteriorated processed vegetable oil, it is also known as “Spanish toxic oil syndrome.” Although the disease has not seen in China, but the cause is not the last clear, can not guarantee that the future is no longer popular, and most patients have skin lesions, so the comprehensive part of the literature, described below.