患儿,男,4岁。患有颌面部中线区多发性缺损畸形,并存在语音障碍、进食困难、经常感冒、喉痛及耳痛症状。出生时见有硬软腭及牙槽突前后向完全裂开、巨唇、分叉舌、下颌骨中线部联合不全,而家族史不详。入院后经口腔外科、儿科、耳鼻喉科及胸外科会诊检查发现:患完全性腭裂;舌体呈分叉状,左右各一(右稍大于左),于舌盲孔平面融合为一体,舌前伸时两个舌头向左右分开;鼻背上有一凹陷,凹陷中有毛发长出;下颌骨前联合处大约有2 cm宽的无牙区,该处牙槽低平菲薄;下唇巨大且前突,红唇凹凸不平,红唇缘失去正常形态,涎液外溢不止;乳牙发育不良,龋齿甚多。此外,还患有脊柱裂、中耳积液,多毛症( Children, male, 4 years old. Suffering from maxillofacial midline multiple defect deformity, and the existence of speech disorders, eating difficulties, often cold, sore throat and otalgia symptoms. At birth, see the hard and soft palate and alveolar process before and after the complete split, giant lips, bifurcation tongue, midline mandibular joint incomplete, and family history unknown. After admission, oral surgery, pediatrics, otolaryngology and thoracic surgery consultation examination found: suffering from complete cleft palate; tongue was bifurcated, left and right one (right slightly larger than the left), the integration of the blind hole in the tongue as a whole, the tongue The two tongues are separated to the left and right when they are stretched out; there is a depression on the back of the nose and hair grows in the depression; the anterior teeth of the mandible is about 2 cm wide in the toothless area where the alveolus is low and flat; Protrusion, red lips uneven, red lips lose the normal form, more than the spillover; milk teeth poorly developed, many dental caries. In addition, there are also spina bifida, middle ear effusion, hirsutism