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１ＣＤ_４４基因的结构、功能及其表达人类ＣＤ４４基因位于１１号染色体短臂上，有２０个高度保守的外显子组成，其中包括１０个组成型外显子和１０个Ｖ区变异性拼接外显子［１，２］。它指导编码合成一族可被ＣＤ４４单克隆抗体所识别的糖蛋白──ＣＤ４４蛋白，而得名。ＣＤ
1CD_44 gene structure, function and expression The human CD44 gene is located on the short arm of chromosome 11 and consists of 20 highly conserved exons, including 10 constitutive exons and 10 V-region variability mosaics. Sub [1,2]. It has been named for the coding and synthesis of a family of glycoproteins known as CD44 monoclonal antibodies, the CD44 protein. CD