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目的检测鼻腔鼻窦内翻性乳头状瘤组织中微血管密度(microvasular density,MVD)的表达,为寻找预测和治疗鼻腔鼻窦内翻性乳头状瘤新方法提供依据。方法选取我院2013~2015年收治的经病例证实的NIP标本30例作为研究对象,采用免疫组化SP法检测10例鼻中膈偏曲矫正术后切除的下鼻甲组织中及30例鼻腔鼻窦内翻性乳头状瘤组织中MVD的表达,进行统计学分析,了解相关性。结果二者组织中MVD分别是25.48±2.94、42.64±7.43相比差异有显著性。结论 MVD可定量反映鼻内翻性乳头状瘤血管生成情况,有可能成为判断鼻内翻性乳头状瘤的发生发展的良好指标
Objective To detect the expression of microvasular density (MVD) in inverted papilloma of the nasal cavity and to provide a basis for finding a new method for predicting and treating inverted papilloma of the nasal cavity and nasal cavity. Methods Thirty cases of NIP specimens confirmed by the case from 2013 to 2015 in our hospital were selected as the research object. Ten cases of nasal turbinate tissue resected after nasal diaphragm correction were examined by immunohistochemical SP method and 30 cases of nasal sinus Inverted papilloma Tissue MVD expression, statistical analysis, to understand the correlation. Results The MVD of the two tissues were 25.48 ± 2.94 and 42.64 ± 7.43, respectively, and the difference was significant. Conclusion MVD can quantitatively reflect the angiogenesis of nasal inverted papilloma and may be a good indicator to judge the occurrence and development of nasal inverted papilloma