考察了聚丙烯酰胺的Ｍａｎｎｉｃｈ反应，由于在反应过程中从反应混合物中分离出羟甲基聚丙烯酰胺，修正了ＭｃＤｏｎａｌｄ提出的反应机理，在给出各单元速度常数和组分微分方程式的基础上，应用泰勒定理计算出反应过程各组浓度变化曲线，据此，对反应过程中出现的凝胶化现象做出了解释。 The Mannich reaction of polyacrylamide was investigated. Since the methylol polyacrylamide was separated from the reaction mixture during the reaction, the reaction mechanism proposed by McDonald was modified. Based on the unit velocity constants and differential equations , The application of Taylor’s theorem to calculate the reaction process of concentration changes in each group curve, accordingly, the phenomenon of gelation reaction process is explained.