目前提到,神经病学异常不是叶酸缺乏的特征性表现。但根据叶酸缺乏的临床经验以及血清和红细胞中叶酸的测定,有一些作者认为叶酸缺乏时的神经病学症侯群和恶性贫血时类似。 Grant(1965)曾意外地发现,10例骨髓中具有巨成红细胞改变(虽未必为贫血)而伴神经病变的患 It is currently mentioned that neuropathological abnormalities are not characteristic of folic acid deficiency. However, according to the clinical experience of folic acid deficiency and the determination of folic acid in serum and erythrocytes, some authors have suggested that neuroprotective disorders in the absence of folic acid are similar to those in pernicious anemia. Grant (1965) had unexpectedly found that in 10 cases of bone marrow with giant erythroid changes (though not necessarily anemia) with neuropathy