感染伯氏疟原虫的小鼠体内疟原虫的数量随时间呈交替性的上升和下降，并与红内期裂体增殖的周期相一致。裂殖体所占百分比在高原虫血症期最高。感染小鼠可死亡或自愈，自愈者体内残存配子体的核缩小或消失 The number of Plasmodium species in mice infected with Plasmodium berghei increased and decreased alternately with time and was consistent with the period of erythrocyte proliferation. The percentage of schizonts was the highest in the poliomyelitis stage. Infected mice can be dead or self-healing, self-healing body with the remaining gametocytes in the nucleus narrowed or disappeared