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为探讨非亲缘非清髓异基因造血干细胞移植 (URD NAPBSCT)在治疗急性白血病中 (AL)的作用 ,1例HLA完全相合的急性淋巴细胞白血病病人接受了URD NAPBSCT治疗。结果病人顺利度过造血抑制期并获得完全性植入 ,移植后发生了皮肤Ⅱ度GVHD和间质性肺炎 ,经治疗后痊愈。结果初步表明 ,URD NAPBSCT较简便安全 ,可为急性白血病提供新的有效治疗手段。
To investigate the role of non-associated non-myeloablative allogeneic hematopoietic stem cell transplantation (URD NAPBSCT) in the treatment of acute leukemia (AL), one patient with HLA-fully matched acute lymphoblastic leukemia was treated with URD NAPBSCT. Results The patient successfully passed the stage of hematopoietic suppression and was completely implanted. After the transplantation, grade Ⅱ GVHD and interstitial pneumonia occurred and healed after treatment. The results initially showed that URD NAPBSCT more simple and safe, can provide new and effective treatment for acute leukemia.