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作者报告了353例口腔黑色斑(OMM)的临床和组织病理数据。 材料与方法 所有病例经活检证实有以下组织病理特征:①基底细胞层、固有层或二者均有黑色素;②无伸长上皮网钉;③无明显黑色素细胞活跃。 结果 353例OMM的平均年龄为43.1岁(1～80岁)。但下唇OMM患者的平均年龄为36.9岁,牙龈OMM患者的平均年龄为40.4岁。女性占63.5％,男性占36.5％。白种人患者占85.3％,黑种人患者占12.3％,其他人种患者占2.4％.OMM的部位分别为下唇33.0％。腭部21.6％,牙龈20.2％,颊粘膜17.9％,其他部位7.2％。OMM的平均大小(157例)为6.8 mm,直径大于10mm者仅占11.7％,颊粘膜OMM的大小几乎是其他部位的2倍(11.3 mm比5.8mm,P=0.0014)。白种人好发于下唇,黑种人好发于颊
The authors reported clinical and histopathological data on 353 cases of oral black plaque (OMM). Materials and methods All cases confirmed by biopsy have the following histopathological features: ① basal cell layer, lamina propria or both have melanin; ② no elongated epithelial net nail; ③ no significant melanoma cells active. Results The average age of 353 OMMs was 43.1 years (range, 1 to 80 years). However, the average age of lower lip OMM patients was 36.9 years, and the average age of gingival OMM patients was 40.4 years. 63.5% of women and 36.5% of men. White patients accounted for 85.3%, black patients accounted for 12.3%, other race patients accounted for 2.4% .OMM sites were lower lip 33.0%. 21.6% of the palate, 20.2% of the gums, 17.9% of the buccal mucosa, and 7.2% of the other parts. The average size of the OMM was 157 (6.8 cases), only 11.7% of the patients were larger than 10 mm in diameter, and OMM in buccal mucosa was almost twice as large in size (11.3 mm vs 5.8 mm, P = 0.0014). Caucasians occur in the lower lip, black people occur in the cheeks