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目的观察B型超声(B超)引导下靶向注射甲氨蝶呤治疗瘢痕妊娠的临床疗效。方法选取2011年1月-2015年2月来该院就诊的子宫瘢痕妊娠患者42例,均采用B超引导下靶向注射甲氨蝶呤治疗。比较治疗前后的血h CG水平、妊娠包块大小、包块外缘距浆膜层厚度及治疗后临床不适的发生率。结果治疗后血h CG水平下降、妊娠包块缩小、包块外缘距浆膜层厚度增加,与治疗前相比差异有统计学意义(P<0.05),治疗后临床不适的发生率较低。结论 B超引导下靶向注射甲氨蝶呤治疗瘢痕妊娠具有较好的临床疗效,减少术中出血量,降低子宫切除率,可在临床广泛推广。
Objective To observe the clinical efficacy of targeted methotrexate in the treatment of scar pregnancy under the guidance of B-mode ultrasound (B-mode ultrasound). Methods Forty-two patients with uterine scar pregnancy treated in our hospital from January 2011 to February 2015 were selected and treated with B-guided methotrexate injection. The levels of blood hCG before and after treatment, the size of the mass of pregnancy, the thickness of the serosa from the outer margin of the mass and the incidence of clinical discomfort after treatment were compared. Results After treatment, the level of blood CG decreased, the mass of pregnancy contracted, the thickness of the outer margin of the mass increased from the serosa layer, which was significantly different from that before treatment (P <0.05). The incidence of clinical discomfort was lower after treatment . Conclusion B-guided targeted methotrexate injection in the treatment of scar pregnancy has good clinical efficacy, reduce intraoperative bleeding and reduce the rate of hysterectomy, can be widely promoted in the clinic.