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目的观察奥明格健脑口服液对改善小鼠记忆作用的影响。方法断乳小鼠,体重12~14g,每组14~16只。把实验动物随机分为正常对照组、高剂量组、中剂量组和低剂量组,连续给样30d,进行跳台和水迷宫试验,以上试验按同样方法重复一次。结果两次小鼠实验表明,灌胃奥明格健脑口服液1mo后,跳台试验中受电击动物数和错误总数,各试验组均低于对照组,其中高剂量试验组显著低于对照组,而且潜伏期显著延长。水迷宫试验中,动物到达终点所需时间和错误总数,高中剂量组试验组均显著低于对照组。结论奥明格健脑口服液具有改善动物记忆的作用。
Objective To observe the effect of Aominginger Jiannei oral liquid on improving the memory of mice. Methods Weanling mice, body weight 12 ~ 14g, each group 14 ~ 16. The experimental animals were randomly divided into normal control group, high-dose group, middle-dose group and low-dose group for continuous 30d, jumping platform and water maze test, the above test repeated in the same way. Results The results of two experiments in mice showed that after being orally administered with Amining Jiannao Oral Liquid for 1 month, the number of animals and the total number of electric shocks in the jumping test were lower in each test group than in the control group, of which the high-dose test group was significantly lower than the control group , But also significantly prolonged incubation period. In the water maze test, the time and number of errors that the animals needed to reach the end were significantly lower in the high and middle dose groups than in the control group. Conclusion Omin Jiannao Oral Liquid has the effect of improving animal memory.