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癌基因表达从不同角度反映了乳腺癌的恶性生物学行为,并引起组织病理学改变,进而形成多种影像学表现.因此,越来越多的学者发现乳腺癌超声表现与分子免疫组化指标之间存在一定相关性,通过乳腺癌的超声征象可以预测某些分子免疫组化指标的表达及其预后.本文主要对乳腺癌超声表现与雌激素受体、孕激素受体、人表皮生长因子受体2及Ki67抗原表达的关系研究进行综述.“,”Oncogene expression reflects the malignant biological behavior of breast cancer from different perspectives, and causes histopathological changes,and thus the formation of a variety of imaging performance. Therefore,more and more scholars have found that there is certain correlation between ultrasonographic morphologic features and molecular immunological index of breast cancer,through ultrasonographic performance of breast cancer we can predict the expression and prognostic of some molecular immunological index. This review summarized previous related studies and explored the correlation of ultrasonography of breast cancer with estrogen receptor,progesterone receptor,human epidermal growth factor receptor 2 and Ki-67.