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目前研究认为幽门螺杆菌 (Hp)的致病性主要与其毒力因子有关。而作为毒力相关因子基因群集的特殊染色体区域—— cag致病岛 (Pathogenicity island) [1 ] ,已成为 Hp致病机制研究中新的热点之一。 cag致病岛编码蛋白的功能经计算机分析 ,推测为毒素及毒素转运功能相关的分泌系?
The current study suggests that the pathogenicity of Helicobacter pylori (Hp) is mainly related to its virulence factors. Pathogenicity island, a special chromosomal region of virulence factor-related gene cluster, has become one of the new hot topics in the pathogenesis of Hp. cag pathogenicity island encoded protein function by computer analysis, presumed toxin and toxin transport function related secretion system?