脑缺血可诱导中枢神经系统神经细胞再生,脑缺血后神经再生常见于海马和SVZ,可能与缺血性脑损伤后的记忆恢复有关。脑缺血后神经再生与兴奋性氨基酸受体、神经营养因子、5-HT、炎症和凋亡等有关,干细胞移植能改善缺血性脑损伤模型动物的神经损伤症状。 Cerebral ischemia can induce the regeneration of nerve cells in the central nervous system. Nerve regeneration after cerebral ischemia is common in hippocampus and SVZ, which may be related to memory recovery after ischemic brain injury. Neuronal regeneration after cerebral ischemia is related to excitatory amino acid receptors, neurotrophic factors, 5-HT, inflammation and apoptosis, and stem cell transplantation can improve the neurological injury symptoms of ischemic brain injury model animals.