秘鲁 1 5株系经基因缺失和修饰处理的缺失霍乱毒素 ( CT)基因及其他毒力决定簇基因构件的霍乱弧菌减毒株 ,也是一个稳定缺乏动力而又不能与同源 DNA进行重组的菌株 ,作者在人体攻击模型中测定了该株的安全性、免疫原性和保护效力。　　受试者为经过严格病史审核及体检的健康志 In Peru, 15 strains of cholera toxin (CT) gene and other virulence determinant-deleted attenuated strains of V. cholerae, which have been genetically deleted and modified, are also a stable strain that lacks motivation and can not be recombined with homologous DNA Strain, the authors measured the safety, immunogenicity and protective efficacy of the strain in a human challenge model. The subjects were health records with strict history examination and physical examination